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Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
The process is highly regulated by cell adhesion molecules, particularly, the addressin also known as MADCAM1. This antigen is known for its role in tissue-specific adhesion of lymphocytes to high endothelium venules. [23] Through these interactions they play a crucial role in orchestrating circulating lymphocytes.
Note 1: Adhesion requires energy that can come from chemical and/or physical linkages, the latter being reversible when enough energy is applied. Note 2: In biology, adhesion reflects the behavior of cells shortly after contact to the surface. Note 3: In surgery, adhesion is used when two tissues fuse unexpectedly. [1]
This allows for homophilic cell–cell adhesion. [18] The β-catenin–α-catenin linked complex at the adherens junctions allows for the formation of a dynamic link to the actin cytoskeleton. [19] Integrins act as adhesion receptors, transporting signals across the plasma membrane in multiple directions. These molecules are an invaluable part ...
Cell motility involves many receptors, crosslinking, bundling, binding, adhesion, motor and other proteins. [16] The process is divided into three steps: protrusion of the leading edge of the cell, adhesion of the leading edge and de-adhesion at the cell body and rear, and cytoskeletal contraction to pull the cell forward.
In cell biology, focal adhesions (also ... One example of their important role is in the immune system, ... [5] Once in place, a focal adhesion remains stationary ...
[5] Synaptic signaling, an integral part of nervous system activity, occurs between neurons and target cells. These target cells can also be neurons or other cell types (i.e. muscle or gland cells). Protocadherins, a member of the cadherin family, mediate the adhesion of neurons to their target cells at synapses otherwise known as synaptic ...
Escherichia coli FimH provides an example of conformation specific immune response which enhances impact on the protein. [19] By studying this particular adhesion, researchers hope to develop adhesion-specific vaccines which may serve as a model for antibody-mediation of pathogen adhesion. [19]