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Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1]
In healthy humans, the half-life of PPIs is about 1 hour (9 hours for tenatoprazole), but the duration of acid inhibition is 48 hours because of irreversible binding to the H,K-ATPase. [82] All the PPIs except tenatoprazole are rapidly metabolized in the liver by CYP enzymes (mostly by CYP2C19 and 3A4). [ 82 ]
The Spanish language does not explicitly demonstrate in its grammar whether an object, either direct or indirect, refers to an animate or inanimate object. Therefore, the use of two clitics is common, although not always required. In this way, clitics can be doubled or "redundant" when two instances occur within the same phrase.
The pronouns yo, tú, vos, [1] él, nosotros, vosotros [2] and ellos are used to symbolise the three persons and two numbers. Note, however, that Spanish is a pro-drop language, and so it is the norm to omit subject pronouns when not needed for contrast or emphasis. The subject, if specified, can easily be something other than these pronouns.
Spanish is a relatively synthetic language with a moderate to high degree of inflection, which shows up mostly in Spanish conjugation. As is typical of verbs in virtually all languages, Spanish verbs express an action or a state of being of a given subject, and like verbs in most Indo-European languages , Spanish verbs undergo inflection ...
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The following is a non-exhaustive list of standardized tests that assess a person's language proficiency of a foreign/secondary language. Various types of such exams exist per many languages—some are organized at an international level even through national authoritative organizations, while others simply for specific limited business or study orientation.
The Versant Spanish Test was used in a study by Blake, et al. (2008) [5] to evaluate whether distance-learning courses are as valid a way to start learning a foreign language as traditional face-to-face classes that meet five times a week with respect to oral proficiency.