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Darier's disease (DD) is a rare, genetic skin disorder. It is an autosomal dominant disorder, that is, if one parent has DD, there is a 50% chance than a child will inherit DD. It was first reported by French dermatologist Ferdinand-Jean Darier in 1889.
Polydactylous longitudinal erythronychia has been most commonly associated with Darier's disease [10] and lichen planus [11] but has also occasionally been associated with acantholytic epidermolysis bullosa, [12] no association, [13] graft-versus-host disease, [14] [15] hemiplegia, [16] and systemic amyloidosis. [11]
Often no specific cause for the eruptions is found. However, it is sometimes linked to underlying diseases and conditions such as: Food (including blue cheese or tomatoes). Contact Dermatitis (i.e. cleaning agents, fabric softeners, etc.) Fungal, Bacterial and Viral infections such as sinusitis, tuberculosis, candidiasis or tinea.
When the cause of sciatica is lumbar disc herniation (90% of cases), [4] most cases resolve spontaneously over weeks to months. [46] Initially treatment in the first 6–8 weeks should be conservative. [4] More than 75% of sciatica cases are managed without surgery. [14] Smokers with sciatica are strongly urged to quit in order to promote ...
Acupuncture is used worldwide as a treatment for sciatica, often successfully, as documented in a meta-analysis published in Frontiers in Neuroscience in 2023. The new trial is an effort to ...
Darier's sign is a change observed after stroking lesions on the skin of a person with systemic mastocytosis or urticaria pigmentosa. [1] In general, the skin becomes swollen, itchy and red. This is a result of compression of mast cells, which are hyperactive in these diseases. These mast cells release inflammatory granules which contain ...
Pain caused by compression or irritation of the sciatic nerve by a problem in the lower back is called sciatica. Common causes of sciatica include the following lower back and hip conditions: spinal disc herniation, degenerative disc disease, lumbar spinal stenosis, spondylolisthesis, and piriformis syndrome. [5]
Constipation is more concerning when there is weight loss or anemia, blood is present in the stool, there is a history of inflammatory bowel disease or colon cancer in a person's family, or it is of new onset in someone who is older. [12] Treatment of constipation depends on the underlying cause and the duration that it has been present. [4]