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A leprostatic agent is a drug that interferes with proliferation of the bacterium that causes leprosy. [1] [2] The following agents are leprostatic agents: [3] acedapsone; clofazimine; dapsone; desoxyfructo-serotonin; diucifon; ethionamide; rifampicin; rifapentine; sulfameter; thalidomide; Leprosy is a chronic infectious disease caused by ...
Leprosy has historically been associated with social stigma, which continues to be a barrier to self-reporting and early treatment. [4] Leprosy is classified as a neglected tropical disease. [21] World Leprosy Day was started in 1954 to draw awareness to those affected by leprosy. [22] [4] The study of leprosy and its treatment is known as ...
Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one [a] of the two species of bacteria that cause Hansen's disease (leprosy), [1] a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
Leprosy, sometimes known as Hansen's disease, is an infectious disease caused by Mycobacterium leprae, an aerobic, acid-fast, rod-shaped mycobacterium. The modern term for the disease is named after the discoverer of the bacterium, Gerhard Armauer Hansen .
Bust of Dr. Armauer Hansen, Botanical garden, University of Bergen, Norway. Gerhard Henrik Armauer Hansen (Norwegian pronunciation: [ˈɡæ̂rhɑɖ ɑrˈmæ̀ʉər ˈhɑ̂nsn̩]; 29 July 1841 – 12 February 1912) was a Norwegian physician, remembered for his identification of the bacterium Mycobacterium leprae in 1873 as the causative agent of leprosy.
Mycobacterium lepromatosis can induce diffuse lepromatous leprosy (DLL), typically known to occur in Mexico and the Caribbean. [5] [6] DLL is a severe form of leprosy which manifests through nerve invasion and extensive skin ulcerations due to massive AFB burden in internal organs. [5]
They concluded that a single dose of a combination of rifampicin, ofloxacin and minocycline is an acceptable and cost-effective alternative regimen for the treatment of single-lesion paucibacillary leprosy and the duration of the standard regimen for multibacillary leprosy could be shortened to 12 months.