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No studies have indicated a long-term negative effect of Botox, though there are possible side effects to be aware of: Swelling, pain, and bruising at the injection site, headache and flu symptoms ...
Popular spots to get Botox include the “crow’s-feet” lines on the outside corners of your eyes, between the eyebrows (where “11 lines” can form), and the forehead.
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Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
Toxic effects of retinoids occur with both acute or prolonged intake, depending on which retinoid is considered. The specific toxicity is related to the mechanism of action as well as exposure. A medical sign of chronic or acute poisoning with retinol is hypervitaminosis A , which includes the presence of painful tender swellings on the long bones.
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