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  2. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    This is a list of drugs and substances that are known or suspected to cause StevensJohnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .

  3. Stevens–Johnson syndrome - Wikipedia

    en.wikipedia.org/wiki/StevensJohnson_syndrome

    StevensJohnson syndrome (SJS) is a milder form of toxic epidermal necrolysis (TEN). [50] These conditions were first recognized in 1922. [27] A classification first published in 1993, that has been adopted as a consensus definition, identifies StevensJohnson syndrome, toxic epidermal necrolysis, and SJS/TEN overlap.

  4. Toxic epidermal necrolysis - Wikipedia

    en.wikipedia.org/wiki/Toxic_epidermal_necrolysis

    Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a type of severe skin reaction. [2] Together with StevensJohnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. [2] Early symptoms include fever and flu-like symptoms. [2] A few days later the skin begins to blister and peel forming painful raw ...

  5. Acute generalized exanthematous pustulosis - Wikipedia

    en.wikipedia.org/wiki/Acute_generalized...

    Studies on the DRESS syndrome, StevensJohnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS/TEN overlap indicate that many individuals are predisposed to develop these reactions to a particular medication based on their genetically determined expression of particular human leukocyte antigen (i.e. HLA) alleles or T-cell receptors ...

  6. Severe cutaneous adverse reactions - Wikipedia

    en.wikipedia.org/wiki/Severe_cutaneous_adverse...

    Stevens-Johnson/toxic epidermal necrolysis overlap syndrome (SJS/TEN); and Acute generalized exanthematous pustulosis (AGEP). The five disorders have similar pathophysiologies , i.e. disease-causing mechanisms, for which new strategies are in use or development to identify individuals predisposed to develop the SCARs-inducing effects of ...

  7. Sulfonamide (medicine) - Wikipedia

    en.wikipedia.org/wiki/Sulfonamide_(medicine)

    Person with StevensJohnson syndrome Allergic urticaria on the skin induced by an antibiotic Sulfonamides have the potential to cause a variety of adverse effects , including urinary tract disorders, haemopoietic disorders, porphyria and hypersensitivity reactions.

  8. Nikolsky's sign - Wikipedia

    en.wikipedia.org/wiki/Nikolsky's_sign

    StevensJohnson syndrome Nikolsky's sign is a clinical dermatological sign , named after Pyotr Nikolsky (1858–1940), a Russian physician who trained and worked in the Russian Empire. The sign is present when slight rubbing of the skin results in exfoliation of the outermost layer.

  9. Erythema multiforme - Wikipedia

    en.wikipedia.org/wiki/Erythema_multiforme

    StevensJohnson syndrome and toxic epidermal necrolysis used to be considered part of the erythema multiforme "spectrum," but EM is now recognized as a fundamentally different condition. [10] In addition to the differing pathogenesis, SJS/TEN also differs in its clinical characteristics, and may be excluded based on clinical characteristics ...