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A generalized tonic–clonic seizure, commonly known as a grand mal seizure or GTCS, [1] is a type of generalized seizure that produces bilateral, convulsive tonic and clonic muscle contractions. Tonic–clonic seizures are the seizure type most commonly associated with epilepsy and seizures in general and the most common seizure associated ...
Tonic-clonic seizures occur with a contraction of the limbs followed by their extension and arching of the back which lasts 10–30 seconds (the tonic phase). A cry may be heard due to contraction of the chest muscles, followed by a shaking of the limbs in unison (clonic phase). Tonic seizures produce constant contractions of the muscles.
Status epilepticus (SE), or status seizure, is a medical condition with abnormally prolonged seizures.It can have long-term consequences, [3] manifesting as a single seizure lasting more than a defined time (time point 1), or 2 or more seizures over the same period without the person returning to normal between them.
Febrile infection-related epilepsy syndrome (FIRES), is onset of severe seizures (status epilepticus) following a febrile illness in someone who was previously healthy. [1] The seizures may initially be focal; however, often become tonic-clonic. [4] Complications often include intellectual disability, behavioral problems, and ongoing seizures ...
A seizure is a sudden change in behavior, movement or consciousness due to abnormal electrical activity in the brain. [3] [6] Seizures can look different in different people. It can be uncontrolled shaking of the whole body (tonic-clonic seizures) or a person spacing out for a few seconds (absence seizures).
Prolonged seizures in the first year of life are the most indicative physical manifestation of DS. [2] DS is diagnosed clinically and genetic testing is recommended if there is any doubt. [2] Due to drug-refractory epilepsy in DS, many other therapies are being explored to prolong the life expectancy of patients. [3]