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Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
The Multiple Sleep Latency Test (MSLT) is a sleep disorder diagnostic tool. It is used to measure the time elapsed from the start of a daytime nap period to the first signs of sleep, called sleep latency. The test is based on the idea that the sleepier people are, the faster they will fall asleep.
Rapid eye movement (REM) sleep is a stage in the sleep cycle when vivid dreaming occurs. REM sleep helps with information processing and consolidation. REM latency (REML) is the amount of time it ...
Sleep onset is the transition from wakefulness into sleep. Sleep onset usually transits into non-rapid eye movement sleep (NREM sleep) but under certain circumstances (e.g. narcolepsy ) it is possible to transit from wakefulness directly into rapid eye movement sleep (REM sleep).
A sleep onset latency of 0 to 5 minutes means severe sleep deprivation, 5 to 10 minutes is "troublesome", 10 to 15 minutes indicates a mild but "manageable" degree of sleep debt, and 15 to 20 minutes is indicative of "little or no" sleep debt. [1]: 341–342
Insufficient quality or quantity of night time sleep [5] Obstructive sleep apnea [6] Misalignments of the body's circadian pacemaker with the environment (e.g., jet lag, shift work, or other circadian rhythm sleep disorders) [7] Another underlying sleep disorder, such as narcolepsy, sleep apnea, [8] idiopathic hypersomnia, or restless legs syndrome
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