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Canine parvovirus (also referred to as CPV, CPV2, or parvo) is a contagious virus mainly affecting dogs and wolves. CPV is highly contagious and is spread from dog to dog by direct or indirect contact with their feces. Vaccines can prevent this infection, but mortality can reach 91% in untreated cases.
Gagnon CA, Allard V, Cloutier G. Canine parvovirus type 2b is the most prevalent genomic variant strain found in parvovirus antigen positive diarrheic dog feces samples across Canada. Can Vet J ...
In Europe, more than a dozen countries also saw "unusually high numbers of cases" of parvovirus B19 in the first quarter of 2024, CDC's alert said. Parvovirus B19 is highly infectious.
Parvovirus B19 will start replicating from anywhere for four to eighteen days. Infected children will be most contagious during this time and before they develop the most notable sign, a red rash on their cheeks, and other symptoms. [4] Since parvovirus B19 is a single stranded DNA virus, replication can only occur in dividing cells. [8]
Schematic diagram of a Parvoviridae virion A diagram of the canine parvovirus's capsid, containing 60 monomers of the capsid protein. Parvovirus virions are 23–28 nanometers (nm) in diameter and consist of the genome enclosed inside a capsid that is icosahedral in shape with a rugged surface. The capsid is composed of 60 structurally ...
A parvovirus B19 infection usually causes no symptoms or a relatively mild illness, like flu-like symptoms, rashes, and joint pains, the CDC says. These are the biggest symptoms to have on your ...
Human parvovirus B19, generally referred to as B19 virus (B19V), parvovirus B19 [1] or sometimes erythrovirus B19, [2] is a known human virus in the family Parvoviridae, genus Erythroparvovirus; it measures only 23–26 nm in diameter. [3] Human parvovirus b19 is a below-species classification of Erythroparvovirus primate1. [4]
AAV capsid proteins contain 12 hypervariable surface regions, with most variability occurring in the threefold proximal peaks, but the parvovirus genome in general presents highly conserved replication and structural genes across serotypes. [67] All of the known serotypes can infect cells from multiple diverse tissue types.