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Polysorbate 80 is a surfactant and solubilizer used in a variety of oral and topical pharmaceutical products. Polysorbate 80 is also an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the making of the antiarrhythmic amiodarone . [ 9 ]
Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate) The number following the 'polysorbate' part is related to the type of major fatty acid associated with the molecule. Monolaurate is indicated by 20, monopalmitate is indicated by 40, monostearate by 60, and monooleate by 80.
Madin Darby Canine Kidney (MDCK) cell protein, MDCK cell DNA, polysorbate 80, cetyltrimethlyammonium bromide, β-propiolactone, phosphate buffer Influenza vaccine Formaldehyde, á-tocopheryl hydrogen succinate, polysorbate 80, sodium deoxycholate, thimerosal, ovalbumin: Influenza vaccine
Docetaxel is a white powder and is the active ingredient available in 20 mg and 80 mg Taxotere single-dose vials of concentrated anhydrous docetaxel in polysorbate 80. [ 16 ] [ 17 ] The solution is a clear brown-yellow containing 40 mg docetaxel and 1040 mg polysorbate 80 per mL.
It was encapsulated in polysorbate 80 coated nanoparticles and intravenously injected. [5] This was a huge breakthrough in the nanoparticle drug delivery field, and it helped advance research and development toward clinical trials of nanoparticle delivery systems.
A highly viscous cubic phase gel made of polysorbate 80, water, and liquid paraffin. Lyotropic liquid crystals result when amphiphiles, which are both hydrophobic and hydrophilic, dissolve into a solution that behaves both like a liquid and a solid crystal. This liquid crystalline mesophase includes everyday mixtures like soap and water. [1] [2]
As well as the active antigen derived from A/California/7/2009 (H1N1), the vaccine contains an immunologic adjuvant AS03 which consists of DL-α-tocopherol (vitamin E), squalene and polysorbate 80. [citation needed] Thiomersal (thimerosal) is added as a preservative. Being manufactured in chicken eggs, it contains trace amounts of egg proteins.
Polysorbate 20 – emulsifier; Polysorbate 40 – emulsifier; Polysorbate 60 – emulsifier; Polysorbate 65 – emulsifier; Polysorbate 80 – emulsifier; Polyvinylpolypyrrolidone – color stabiliser; Pomegranate seeds (though some consider these a fruit, not a spice) – Ponceau 4R – color (FDA: Ext D&C Red #8) Ponceau 6R – color; Ponceau ...