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Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor. [1] It is used to treat various eye diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and infections inside the eye such as endophthalmitis. [1]
Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes, immune function and reproductive development. [3]
Laser surgery is a treatment option which uses a laser beam to seal off damaged blood vessels in the retina. [9] Anti-vascular endothelial growth factor (VEGF) drugs like Avastin and Lucentis have also been shown to repair retinal hemorrhaging in diabetic patients and patients with hemorrhages associated with new vessel growth. [10] [11]
Bevacizumab however is not FDA approved for treatment of macular degeneration. A controversy in the UK involved the off-label use of cheaper bevacizumab over the approved, but expensive, ranibizumab. [81] Ranibizumab is a smaller fragment, Fab fragment, of the parent bevacizumab molecule specifically designed for eye injections. [82]
retinol, retinal, tretinoin (retinoic acid), isotretinoin, and alitretinoin: Second generation: Synthetic analogs formulated for oral dosing. There are no topically available second generation formulations of retinoids. etretinate and its metabolite acitretin: Third generation: Retinoidal benzoic acid derivatives: adapalene, bexarotene, and ...
Branch retinal artery occlusion BRVO Branch retinal vein occlusion Cat Cataract: CLAPC/CLIPC Contact lens associated/induced papillary conjunctivitis CLARE Contact lens associated red eye CLPU Contact lens associated peripheral ulcer CNS Central nervous system CNV Choroidal neovascularization: CRAO Central retinal artery occlusion CRVO