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A resection margin or surgical margin is the margin of apparently non-tumorous tissue around a tumor that has been surgically removed, called "resected", in surgical oncology. The resection is an attempt to remove a cancer tumor so that no portion of the malignant growth extends past the edges or margin of the removed tumor and surrounding tissue.
The MasSpec Pen was designed to assist in the detection of positive surgical margins during solid tumor debulking procedures to assist in the complete excision of cancer surgeries. The device was initially used to analyze 253 human tissue biopsies, including normal and cancerous breast, lung, ovary, and thyroid tissues. [ 1 ]
The risk of subsequent recurrent disease has been considered highest in those tumours where the pathology shows tumour at the margins of the resection (positive margins), multiple involved regional lymph nodes, and extension of the tumour outside of the capsule of the lymph node (extracapsular extension), based on historical experience with ...
The objective of cancer screening is to detect cancer before symptoms appear, involving various methods such as blood tests, urine tests, DNA tests, and medical imaging. [1] [2] The purpose of screening is early cancer detection, to make the cancer easier to treat and extending life expectancy. [3]
Complete circumferential peripheral and deep margin assessment (CCPDMA) is the preferred method for the removal of certain cancers, especially skin cancers. [ 1 ] [ 2 ] There are two forms of CCPDMA surgery: Mohs surgery and surgical excision coupled with margin assessment.
A diagram of a local resection of early stage colon cancer A diagram of local surgery for rectal cancer Margins of a colonic resection. At an early stage, colorectal cancer may be removed during a colonoscopy using one of several techniques, including endoscopic mucosal resection or endoscopic submucosal dissection. [5]