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From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [ 117 ] and $13 billion a year at its peak, [ 118 ] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years."
The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. [12] The manufacturer Pfizer reported sales of US$12.4 billion in 2008. [13] Patient compliance with statin usage is problematic despite robust evidence of the benefits. [14] [15]
In addition to these interactions atorvastatin and rosuvastatin also form unique hydrogen bonds between Ser 565 residue and either a carbonyl oxygen atom (atorvastatin) or a sulfone oxygen atom (rosuvastatin).
Atorvastatin. Rosuvastatin. You may be prescribed a statin for a short period of time, or be prescribed a statin alongside other treatments or medications. Statin therapy isn’t for everyone, though.
Statins are a type of medication that help lower low-density lipoprotein (LDL) cholesterol — or “bad” cholesterol — in the body. This helps keep the arteries clear so blood has an easier ...
Bruce D. Roth is an American organic and medicinal chemist who trained at Saint Joseph's College, Iowa State University and the University of Rochester, and, at the age of 32, discovered atorvastatin, the statin-class drug sold as Lipitor that would become the largest-selling drug in pharmaceutical history (as of 2003).
The musician shared the story of how he and his brothers were filming a YouTube video before taking the stage at a concert in 2007, but an accident resulted in an injury so severe that he needed ...
The video both opens and ends on the street outside the building. It received an award from MTV in the category of Video of the Year at the 1995 MTV Europe Music Awards. [20] Robert Del Naja told The Guardian in 2010, "The 'Protection' video shoot was the most agonising by far. We were lucky to work with Michel Gondry but I can safely say it ...