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Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Adverse effects, like therapeutic effects of drugs, are a function of dosage or drug levels at the target organs, so they may be avoided or decreased by means of careful and precise pharmacokinetics, the change of drug levels in the organism in function of time after administration. Adverse effects may also be caused by drug interaction. This ...
Cephalosporins, but only these with a methylthiotetrazole side chain or a methylthiodioxotriazine ring; thought to be due to common N-methylthiotetrazole metabolite, which is similar in structure to disulfiram. [8] Such drugs include cefamandole, cefmenoxime, cefmetazole, cefonicid, cefoperazone, cefotetan, ceftriaxone, and latamoxef (moxalactam).
Beneficial side effects are less common; some examples, in many cases of side-effects that ultimately gained regulatory approval as intended effects, are: Bevacizumab ( Avastin ), used to slow the growth of blood vessels, has been used against dry age-related macular degeneration , as well as macular edema from diseases such as diabetic ...
Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).
An adventure is an exciting experience or undertaking that is typically bold, sometimes risky. [1] Adventures may be activities with danger such as traveling , exploring , skydiving , mountain climbing , scuba diving , river rafting , or other extreme sports .
The U.S. Department of Energy has zeroed in on three regions of the country it has determined are in major need of new electric transmission infrastructure and eligible for future federal funding ...
Israeli Prime Minister Benjamin Netanyahu successfully underwent surgery to have his prostate removed, hospital officials said Sunday. The 75-year-old leader, who has had a series of health issues ...