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  2. Retinoblastoma - Wikipedia

    en.wikipedia.org/wiki/Retinoblastoma

    Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, [2] the light-detecting tissue of the eye. [3] It is the most common primary malignant intraocular cancer in children, especially those under 3 years old.

  3. Eye neoplasm - Wikipedia

    en.wikipedia.org/wiki/Eye_neoplasm

    Retinoblastoma - Strabismus (crossed eyes), a whitish or yellowish glow through the pupil, decreasing/loss of vision, sometimes the eye may be red and painful. Retinoblastoma can occur in one or both eyes. This tumor occurs in babies and young children. It is called RB for short.

  4. Brenda Gallie - Wikipedia

    en.wikipedia.org/wiki/Brenda_Gallie

    This eventually led to the discovery of a new therapy for retinoblastoma. [3] She discovered the fundamental principles of tumor suppressor genes and developed a new methodology to identify the RB1 gene. [1] These tests accurately identified children at risk of developing retinoblastoma before they are born. [4]

  5. Bravery award for girl, 4, with eye cancer - AOL

    www.aol.com/bravery-award-girl-4-eye-125310262.html

    A four-year-old girl who had her eye removed and replaced with a prosthetic one due to cancer has been recognised for her bravery. Ella, from Hull, was diagnosed with bilateral retinoblastoma in ...

  6. Photo taken with iPhone reveals toddler's eye cancer - AOL

    www.aol.com/article/2015/05/11/photo-taken-with...

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  7. Trilateral retinoblastoma - Wikipedia

    en.wikipedia.org/wiki/Trilateral_retinoblastoma

    Trilateral retinoblastoma (TRb) is a malignant midline primitive neuroectodermal tumor occurring in patients with inherited uni- or bilateral retinoblastoma.In most cases trilateral retinoblastoma presents itself as pineoblastoma (pineal TRb).

  8. How the Iowa high school basketball community stepped up ...

    www.aol.com/iowa-high-school-basketball...

    At four years old, Brooklynn was diagnosed with retinoblastoma, cancer of the eye. As it turns out, it was Amani who sounded the alarm first. It all tracks back to Snapchat, and the two sisters ...

  9. Two-hit hypothesis - Wikipedia

    en.wikipedia.org/wiki/Two-hit_hypothesis

    In the children with inherited retinoblastoma, the first mutation in what later came to be identified as the RB1 gene, was inherited, the second one acquired. In non-inherited retinoblastoma, instead two mutations, or "hits", had to take place before a tumor could develop, explaining the later onset.