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On 23 January 2006, an FDA advisory panel voted 11 to 3 to recommend the approval of an OTC formulation of orlistat, to be sold under the brand name Alli by GlaxoSmithKline. [41] Approval was granted on 7 February 2007, [42] and Alli became the first weight loss drug officially sanctioned by the U.S. government for over-the-counter use. [43]
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
In January 2010, a similar alert was issued for counterfeit versions of the over-the-counter weight loss drug Alli sold over the Internet. Instead of the active ingredient orlistat, the counterfeit drugs contain sibutramine, and at concentrations at least twice the amount recommended for weight loss. [43]
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When it comes to losing weight, there are no shortage of unproven recommendations to choose from: fad diets like the carnivore diet or GOLO diet; juice cleanses and vitamin injections; plus a host ...
Weight loss. The proof? A 2017 systematic review and meta-analysis looked into 12 randomized controlled trials with upwards of 600 men and women with overweight or obesity. ... If you’re in the ...
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