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In medicine, the urea-to-creatinine ratio (UCR [1]), known in the United States as BUN-to-creatinine ratio, is the ratio of the blood levels of urea (mmol/L) and creatinine (Cr) (μmol/L). BUN only reflects the nitrogen content of urea (MW 28) and urea measurement reflects the whole of the molecule (MW 60), urea is just over twice BUN (60/28 ...
Blood urea nitrogen (BUN) is a medical test that measures the amount of urea nitrogen found in blood. The liver produces urea in the urea cycle as a waste product of the digestion of protein . Normal human adult blood should contain 7 to 18 mg/dL (0.388 to 1 mmol/L) of urea nitrogen. [ 1 ]
Measurements of urea and creatinine (Cr) in the blood are used to assess renal function. For historical reasons, the lab test measuring urea is known as "blood urea nitrogen" (BUN) in the US. The BUN:Cr ratio is a useful measure in determining the type of azotemia and will be discussed in each section below. A normal BUN:Cr is equal to 15. [3]
As the blood urea nitrogen (BUN) level increases, patients might develop uremic stomatitis. Uremic stomatitis appears as a pseudo membrane or frank ulcerations with redness and a pultaceous coat in the mouth. These lesions could be related to high BUN level (>150mg/dL), and disappear spontaneously when the BUN level is reduced with medical ...
The blood urea nitrogen (BUN) test is a measure of the amount of nitrogen in the blood that comes from urea. It is used as a marker of renal function , though it is inferior to other markers such as creatinine because blood urea levels are influenced by other factors such as diet, dehydration, [ 35 ] and liver function.
Along with UUN, values for BUN, protein content of diet, enteral or parenteral nutrition, and notable outputs other than urine (gastric residual, fistula output, drainages) are needed to calculate nitrogen balance. Nitrogen Balance = Protein intake/6.25- (UN + 4*) * For average loss via sweat and feces.
Outside the United States, blood tests made up of the majority of the same biochemical tests are called urea and electrolytes (U&E or "U and Es"), or urea, electrolytes, creatinine (UEC or EUC or CUE), and are often referred to as 'kidney function tests' as they also include a calculated estimated glomerular filtration rate. The BMP provides ...
An alternative estimation of kidney function can be made when interpreting the blood plasma concentration of creatinine along with that of urea. BUN-to-creatinine ratio (the ratio of blood urea nitrogen to creatinine) can indicate other problems besides those intrinsic to the kidney; for example, a urea concentration raised out of proportion to ...