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The American Urological Association recommends that you get a baseline PSA test between ages 45 and 50, but screening can start at age 40 for those at a higher risk for prostate cancer, such as ...
Men without prostate cancer typically have PSA levels of under 4 nanograms per milliliter (ng/mL), according to the American Cancer Society. PSA levels between 4 and 10 suggest you could have ...
Prostate-specific antigen. Prostate-specific antigen (PSA) is secreted by the epithelial cells of the prostate gland and can be detected in a sample of blood. [14] PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. [15]
Prostate cancer cells generally have variable or weak staining for PSA, due to the disruption of their normal functioning. Thus, individual prostate cancer cells produce less PSA than healthy cells; the raised serum levels in prostate cancer patients is due to the greatly increased number of such cells, not their individual activity.
Prostate cancer is the second most common cause of cancer death among men, according to the American Cancer Society. This year, the organization projects that about 300,000 new cases will be ...
The Scandinavian Prostate Cancer Group Study-4 (SPGS-4) randomized 695 men (mean age 65 years) to observation versus radical prostatectomy; 5% were diagnosed through PSA based screening, 3 of 4 had palpable disease, and the mean PSA level was 13 ng/ml at diagnosis. [9]