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Therefore, all patients receiving TPN must also receive biotin at the recommended daily dose, especially if TPN therapy is expected to last more than 1 week. All hospital pharmacies currently include biotin in TPN preparations. [2] Protein deficiency (not certain): A shortage of proteins involved in biotin homeostasis can cause biotin deficiency.
Discover what this essential B vitamin can do for your body and whether you need more in your diet.
Mutations in the BTD gene cause biotinidase deficiency. Biotinidase is the enzyme that is made by the BTD gene. Many mutations that cause the enzyme to be nonfunctional or to be produced at extremely low levels have been identified. Biotin is a vitamin that is chemically bound to proteins. (Most vitamins are only loosely associated with proteins.)
Signs of a biotin deficiency may appear gradually, per the NIH. In the later stages, a biotin deficiency can cause: Hair thinning. Hair loss. A scaly, red rash around orifices. Dry, red eyes ...
Weight loss medications that are known as “lipase inhibitors” can cause steatorrhea, says Dr. Shanker-Patel. ... But it also typically leads to greasy, loose stools, and sometimes diarrhea. ...
Subclinical deficiency can cause mild symptoms, such as hair thinning, brittle fingernails, or skin rash, typically on the face. [2] [4] Aside from inadequate dietary intake (rare), biotin deficiency can be caused by a genetic disorder that affects biotin metabolism. The most common among these is biotinidase deficiency.
In fact, pale-colored stool can be the result of something you’ve eaten or a medication you are taking. “Many things can change the color of stool, including food, medication, vitamins as well ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Biotinidase Identifiers Symbol BTD NCBI gene 686 HGNC 1122 OMIM 609019 RefSeq NM_000060 UniProt P43251 Other data EC number 3.5.1.12 Locus Chr. 3 p25 Search for Structures Swiss-model Domains InterPro Biotinidase (EC 3.5.1.12, amidohydrolase ...