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7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [1] [2] It is a non-selective antagonist of the adenosine receptors. [1] [2] The compound may slow the progression of myopia (nearsightedness).
Methylxanthines are chemical compounds which are derivatives of xanthine with one or more methyl groups, including: One methyl group: 1-Methylxanthine;
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The systematic name of this enzyme class is S-adenosyl-L-methionine:7-methylxanthine N3-methyltransferase. Other names in common use include monomethylxanthine methyltransferase , MXMT , CTS1 , CTS2 , and S-adenosyl-L-methionine:7-methylxanthine 3-N-methyltransferase .
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IBMX (3-isobutyl-1-methylxanthine), like other methylxanthine derivatives, is both a: . competitive non-selective phosphodiesterase inhibitor [1] which raises intracellular cAMP, activates PKA, inhibits TNFα [2] [3] and leukotriene [4] synthesis, and reduces inflammation and innate immunity, [4] and