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Lisinopril/hydrochlorothiazide, sold under the brand name Zestoretic among others, is a fixed-dose combination medication used for the treatment of high blood pressure (hypertension). [2] It contains lisinopril , an ACE inhibitor , and hydrochlorothiazide , a diuretic .
Lisinopril works by inhibiting the renin–angiotensin–aldosterone system. [7] Lisinopril was patented in 1978 and approved for medical use in the United States in 1987. [7] [11] It is available as a generic medication. [7] In 2022, it was the third most commonly prescribed medication in the United States, with more than 82 million prescriptions.
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In April, Teva offered to acquire Mylan for $40 billion, [41] only a fortnight after Mylan offered to buy Perrigo for $29 billion. [42] Teva's offer for Mylan was contingent on Mylan abandoning its pursuit of Perrigo. [43] Mylan stated in June 2015 that Teva's disclosure that it had a 1.35 percent stake in Mylan violated US antitrust rules. [44]