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In the field of molecular biology, the ETS (E26 transformation-specific [2] or Erythroblast Transformation Specific [3]) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, [4] 27 in the mouse, 10 in Caenorhabditis elegans and 9 in Drosophila.
Ets1 directly interacts with various transcription factors. Their interaction results in formation of multiprotein complexes. When Ets1 interacts with other transcription factors (Runx1, Pax5, TFE3, and USF1) its final effect on transcription depends on whether C-terminal domain is phosphorylated.
2114 23872 Ensembl ENSG00000157557 ENSMUSG00000022895 UniProt P15036 P15037 RefSeq (mRNA) NM_001256295 NM_005239 NM_011809 RefSeq (protein) NP_001243224 NP_005230 NP_035939 Location (UCSC) Chr 21: 38.81 – 38.82 Mb Chr 16: 95.5 – 95.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene. The protein encoded by this ...
SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene. [5] [6] [7] PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator of PSA (MIM 176820) expression.[supplied by OMIM] [7]
13710 Ensembl ENSG00000163435 ENSMUSG00000003051 UniProt P78545 Q3UPW2 RefSeq (mRNA) NM_001114309 NM_004433 NM_001163131 NM_007921 RefSeq (protein) NP_001107781 NP_004424 NP_001156603 NP_031947 Location (UCSC) Chr 1: 202.01 – 202.02 Mb Chr 1: 135.18 – 135.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse E74 like ETS transcription factor 3 is a protein that in humans is encoded ...
ERG (ETS-related gene) is an oncogene. [ 5 ] [ 6 ] [ 7 ] ERG is a member of the ETS (erythroblast transformation-specific) family of transcription factors. [ 8 ] The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator.
The protein encoded by this gene is a member of an epithelium-specific subclass of the ETS transcription factor family.In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate.
Pages in category "Transcription factors" ... ETS transcription factor family; Ets variant 2; Ets variant 5; ETS1; ETS2; ETV1; ETV4; ETV6; F. FACT (biology) Farnesoid ...