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The human virome is the total collection of viruses in and on the human body. [1] [2] [3] Viruses in the human body may infect both human cells and other microbes such as bacteria (as with bacteriophages). [4] Some viruses cause disease, while others may be asymptomatic.
A second defence of vertebrates against viruses is called cell-mediated immunity and involves immune cells known as T cells. The body's cells constantly display short fragments of their proteins on the cell's surface, and, if a T cell recognises a suspicious viral fragment there, the host cell is destroyed by 'killer T' cells and the virus ...
Prior to entry, a virus must attach to a host cell. Attachment is achieved when specific proteins on the viral capsid or viral envelope bind to specific proteins called receptor proteins on the cell membrane of the target cell. A virus must now enter the cell, which is covered by a phospholipid bilayer, a cell's natural barrier to the outside ...
See also Comparison of computer viruses. This is an alphabetical list of genera of biological viruses. It includes all genera and subgenera of viruses listed by the International Committee on Taxonomy of Viruses (ICTV) 2022 release. [1] For a list of virus families and subfamilies, see List of virus families and subfamilies.
Typical sites of virus entry into the body: The first steps of viral infection is determined by the site at which the virus implants into the body. This would subsequently dictate the mechanisms of viral pathogenesis. Transmission from a host with an infection to a second host; Entry of the virus into the body; Local replication in susceptible ...
White blood cells surround and consume the virus using a mechanism known as phagocytosis [2] (a type of endocytosis) [3] within the extracellular matrix to reduce and fight the infection. The components within the white blood cell are responsible for destroying the virus and recycling its components for the body to use. [citation needed]
Gamma phage, an example of virus particles (visualised by electron microscopy) Virology is the scientific study of biological viruses.It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, their interaction with host organism physiology and immunity, the diseases they ...
This specificity restricts the virus to a very limited type of cell. For example, the human immunodeficiency virus (HIV) infects only human T cells, because its surface protein, gp120, can only react with CD4 and other molecules on the T cell's surface. Plant viruses can only attach to plant cells and cannot infect animals.