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Lugol's iodine is a liquid made up of two parts potassium iodide for every one part elemental iodine in water. [8] Lugol's iodine was first made in 1829 by the French physician Jean Lugol. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] [10] Lugol's iodine is available as a generic medication and over the ...
Like other iodide salts, KI forms triiodide (I − 3) when combined with elemental iodine. KI (aq) + I 2 (s) → KI 3 (aq) Unlike I 2, I − 3 salts can be highly water-soluble. Through this reaction, iodine is used in redox titrations. Aqueous KI 3 (Lugol's iodine) solution is used as a disinfectant and as an etchant for gold surfaces.
Iodine is a chemical element with many uses in medicine, depending on the form. Elemental iodine and iodophors are topical antiseptics. [2] Iodine, in non-elemental form, functions as an essential nutrient in human biology (see iodine in biology). [3] Organic compounds containing iodine are also useful iodinated contrast agents in X-ray imaging ...
USP Tincture of Iodine is defined in the U.S. National Formulary (NF) as containing in each 100 mL, 1.8 to 2.2 grams of elemental iodine, and 2.1 to 2.6 grams of sodium iodide. Alcohol is 50 mL, and the balance is purified water. This "2% free iodine" solution has 0.08 mol/L of I 2, which provides about 1 mg of free iodine per 0.05 mL drop. The ...
It is synthesized by mixing the PVP polymer with iodine (I 2), allowing the two to react. [21] It is soluble in cold and mild-warm water, ethyl alcohol, isopropyl alcohol, polyethylene glycol, and glycerol. Its stability in solution is much greater than that of tincture of iodine or Lugol's solution.
This allows Lugol's iodine to be produced in strengths varying from 2% to 15% iodine. Elemental iodine (I 2) is poisonous if taken orally in large amounts; 2–3 grams is a lethal dose for an adult human. [71] [72] Iodine vapor is very irritating to the eye, to mucous membranes, and in the respiratory tract.
properly diluted chlorine preparations (f.e. Dakin's solution, 0.5% sodium or potassium hypochlorite solution, pH-adjusted to pH 7–8, or 0.5–1% solution of sodium benzenesulfochloramide (chloramine B)), some; iodine preparations, such as iodopovidone in various galenics (ointment, solutions, wound plasters), in the past also Lugol's solution,
But free iodine, even in Lugol's, is not safe in certain concentrations and quantities. Yes, the dose makes the poison, but a 2-3 grams of free iodine (100-150 mL of 2% Lugol's) would presumably have severe toxicity, even lethality. 10 mL at 5% (representing about 500 mg free iodine) can burn mucosa in the stomach. . Lower doses and ...
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