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  2. New treatment may slow ALS, with help from Ice Bucket ... - AOL

    www.aol.com/treatment-may-slow-als-help...

    An experimental medication may slow the progression of amyotrophic lateral sclerosis, or ALS, researchers reported Wednesday. The research was supported in part by donations from the Ice Bucket ...

  3. Experimental treatment pushed by ALS patients gets day ... - AOL

    www.aol.com/news/experimental-treatment-pushed...

    NurOwn is the clearest test yet of how far the agency may be willing to bend to approve a new medicine for a rare and deadly condition with few treatment options. ALS gradually destroys nerve ...

  4. Ozanezumab - Wikipedia

    en.wikipedia.org/wiki/Ozanezumab

    Ozanezumab is a monoclonal antibody designed for the treatment of ALS and multiple sclerosis. [1] Ozanezumab targets a protein called Neurite Outgrowth Inhibitor (NOGO-A) or Reticulon 4 (RTN4). NOGO-A is a protein that in humans is encoded by the RTN4 gene that has been identified as an inhibitor of neurite outgrowth specific to the central ...

  5. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    ALS is the most common form of the motor neuron diseases. [8] ALS often presents in its early stages with gradual muscle stiffness, twitches, weakness, and wasting. [3] Motor neuron loss typically continues until the abilities to eat, speak, move, and, lastly, breathe are all lost. [3]

  6. ALS patients with months to live are fighting for better ...

    www.aol.com/news/als-patients-months-live...

    ALS patients experience severe symptoms as the fatal, rare disease progresses. Patients shared how they're fighting for better treatment to be available faster.

  7. Edaravone - Wikipedia

    en.wikipedia.org/wiki/Edaravone

    Edaravone, sold under the brand name Radicava among others, is a medication used to treat stroke and amyotrophic lateral sclerosis (ALS). [ 4 ] [ 5 ] It is given by intravenous infusion [ 4 ] and by mouth .

  8. ALS Therapy Development Institute - Wikipedia

    en.wikipedia.org/wiki/ALS_Therapy_Development...

    The institute has raised and spent more than $100 million on research into effective treatments for ALS and practices open-source science. [19] After the discovery that the multiple sclerosis drug Gilenya might also be a treatment for ALS, the Institute enrolled 30 people in a Phase 2A clinical trial the drug in 2013, though it did not progress further.

  9. FDA advisers vote against experimental ALS treatment ... - AOL

    www.aol.com/news/fda-advisers-vote-against...

    In the last year, the FDA has approved two new drugs for ALS, after a nearly 20-year drought of new options. The approvals followed intense lobbying by advocacy groups.

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