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The total cardiomyocyte growth is given by: λ = λ e ⋅ F λ g {\displaystyle \lambda =\lambda ^{e}\cdot F\lambda ^{g}\,} The above model reveals a gradual dilation of the myocardium , especially the ventricular myocardium, to support the blood volume overload in the chambers.
Also, cardiomyocyte proliferation and regeneration has been demonstrated to occur in various neonatal mammals in response to injury in the first week of life. [ 5 ] [ 6 ] Current research aims to further understand the biological mechanism underlying cardiomyocyte proliferation in hopes to turn this capability back on in adults in order to ...
Cardiomyopathy is a group of primary diseases of the heart muscle. [1] Early on there may be few or no symptoms. [1] As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. [1]
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Its cells are embryologically and biologically similar to the endothelial cells that line blood vessels. The endocardium also provides protection to the valves and heart chambers. [1] The endocardium underlies the much more voluminous myocardium, the muscular tissue responsible for the contraction of the heart.
The lack of oxygen (hypoxia) causes cell death in a localized area which is perfused by blood vessels failing to deliver primarily oxygen, but also other important nutrients. While ischemia in most tissues of the body will cause coagulative necrosis, in the central nervous system ischemia causes liquefactive necrosis , as there is very little ...
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Image of a myocardial action potential. Effective refractory period in green. In electrocardiography, during a cardiac cycle, once an action potential is initiated, there is a period of time that a new action potential cannot be initiated.