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Echinocyte (from the Greek word echinos, meaning 'hedgehog' or 'sea urchin'), in human biology and medicine, refers to a form of red blood cell that has an abnormal cell membrane characterized by many small, evenly spaced thorny projections. [1] [2] A more common term for these cells is burr cells.
Individuals with a single mutation in one of the spectrin genes are usually asymptomatic, but those who are homozygotes or are compound heterozygotes (i.e. they are heterozygous for two different elliptocytosis-causing mutations) have sufficient cell membrane instability to have a clinically significant haemolytic anaemia. [citation needed]
Parietal epithelial cell (PEC) Podocyte; Angioblast → Endothelial cell; Mesangial cell. Intraglomerular; Extraglomerular; Juxtaglomerular cell; Macula densa cell; Stromal cell → Interstitial cell → Telocytes; Kidney proximal tubule brush border cell; Kidney distal tubule cell; Connecting tubule cells; α-intercalated cell; β-intercalated ...
A germ layer is a primary layer of cells that forms during embryonic development. [1] The three germ layers in vertebrates are particularly pronounced; however, all eumetazoans ( animals that are sister taxa to the sponges ) produce two or three primary germ layers.
Cells differentiate into an outer layer of cells called the trophoblast, and an inner cell mass. With further compaction the individual outer blastomeres, the trophoblasts, become indistinguishable. They are still enclosed within the zona pellucida. This compaction serves to make the structure watertight, containing the fluid that the cells ...
Acanthocyte-like cells may be found in hypothyroidism, after splenectomy, and in myelodysplasia. [12] Acanthocytes should be distinguished from echinocytes, which are also called 'burr cells', which although crenated are dissimilar in that they have multiple, small, projecting spiculations at regular intervals on the cell membrane.
The mesoderm aids in the production of cardiac muscle, skeletal muscle, smooth muscle, tissues within the kidneys, and red blood cells. The ectoderm produces tissues within the epidermis and aids in the formation of neurons within the brain, and melanocytes. The proceeding graph represents the products produced by the three germ layers.
A lineage relationship to other cell types has been proposed, including smooth muscle cells, [18] neural cells, [18] NG2 glia, [19] muscle fibers, adipocytes, as well as fibroblasts [20] and other mesenchymal stem cells. However, whether these cells differentiate into each other is an outstanding question in the field.