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  2. Huntington's disease - Wikipedia

    en.wikipedia.org/wiki/Huntington's_disease

    Predictive testing for Huntington's disease has been available via linkage analysis (which requires testing multiple family members) since 1986 and via direct mutation analysis since 1993. [68] At that time, surveys indicated that 50–70% of at-risk individuals would have been interested in receiving testing, but since predictive testing has ...

  3. Nancy Wexler - Wikipedia

    en.wikipedia.org/wiki/Nancy_Wexler

    Nancy Wexler (born 19 July 1945) [1] FRCP MEASA is an American geneticist and the Higgins Professor of Neuropsychology in the Departments of Neurology and Psychiatry of the Columbia University College of Physicians and Surgeons, best known for her involvement in the discovery of the location of the gene that causes Huntington's disease.

  4. James F. Gusella - Wikipedia

    en.wikipedia.org/wiki/James_F._Gusella

    Gusella was a founding director of the Center for Human Genetic Research (now known as the Center for Genomic Medicine) at Massachusetts General Hospital in 2003. [10] Gusella and David Housman were among the founders of Integrated Genetics (now part of Genzyme), who introduced the first diagnostic test for Huntington's disease in 1986. [5]

  5. Do You Really Want to Know? - Wikipedia

    en.wikipedia.org/wiki/Do_You_Really_Want_to_Know?

    The main subjects of the film are Jeff Carroll, a US Army Veteran and Huntington's disease researcher from Washington; Dr. John Roder, a renowned cancer specialist at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto; Theresa Monahan of Ohio, who was among the first Americans to undergo predictive testing for Huntington's disease in 1988, and Dr. Michael R. Hayden, who ...

  6. Lead time bias - Wikipedia

    en.wikipedia.org/wiki/Lead_time_bias

    For example, the genetic disorder Huntington's disease is diagnosed when symptoms appear at around 50, and the person dies at around 65. The typical patient, therefore, lives about 15 years after diagnosis. A genetic test at birth makes it possible to diagnose this disorder earlier.

  7. Carol Carr - Wikipedia

    en.wikipedia.org/wiki/Carol_Carr

    Huntington's disease is an autosomal dominant disorder, inherited from Carol Carr's husband, Hoyt Scott. Hoyt, a factory worker, had lost a sister to the disease as well as a brother, who committed suicide after being diagnosed. Hoyt's condition deteriorated and he died unable to move, swallow, or speak in 1995.

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