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Most SVTs are unpleasant rather than life-threatening, although very fast heart rates can be problematic for those with underlying ischemic heart disease, or the elderly. Episodes can be treated when they occur by Valsalva maneuver , adenosine injection or taking a AV node blocking agent as pill-in-pocket, but regular medication may also be ...
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
[9] [10] Chronic stress, and a lack of coping resources available, or used by an individual, can often lead to the development of psychological issues such as delusions, [11] depression and anxiety (see below for further information). [12] Chronic stress also causes brain atrophy, which is the loss of neurons and the connections between them ...
The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.
Research has found that major life events are somewhat less likely to be major causes of stress, due to their rare occurrences. [10] The length of time since occurrence and whether or not it is a positive or negative event are factors in whether or not it causes stress and how much stress it causes.
The neurogenesis hypothesis of depression gained popularity due to the large number of correlative studies which indicate a relationship between impaired hippocampal neurogenesis and depression. For example, reduced hippocampal volume is associated with depression, which impaired neurogenesis may contribute to. [6] Conflicting evidence
Risk factors for mental illness include psychological trauma, adverse childhood experiences, genetic predisposition, and personality traits. [7] [8] Correlations between mental disorders and substance use are also found to have a two way relationship, in that substance use can lead to the development of mental disorders and having mental disorders can lead to substance use/abuse.
The diathesis-stress model, also known as the vulnerability–stress model, is a psychological theory that attempts to explain a disorder, or its trajectory, as the result of an interaction between a predispositional vulnerability, the diathesis, and stress caused by life experiences.