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Bactericidal permeability-increasing protein (BPI) is a 456-residue (~50kDa) protein that is part of the innate immune system, coded for in the human by the BPI gene. [ 1 ] [ 2 ] It belongs to the family of lipid-binding serum glycoproteins .
BPI-16350 is a small molecule CDK4/6 inhibitor that is being studied for the treatment of cancer. [ 1 ] [ 2 ] It has a similar structure to abemaciclib but is more selective for CDK4/6 over CDK9 according to preclinical research.
The BPI fold creates apolar binding pockets that can interact with hydrophobic and amphipathic molecules, such as the acyl carbon chains of lipopolysaccharide found on Gram-negative bacteria, but members of this family may have many other functions. BPIFB2 is a member of the BPI-fold gene family and the BPI/LBP/PLUNC protein superfamily
The commercial mission is set to launch from Rocket Lab Launch Complex 1 on October 19, 2024, for a confidential customer. This marks the company’s fastest turnaround, achieving the launch in ...
Rocket Lab's flagship rocket is the Electron, which is the second-most-used orbital rocket in the U.S., behind SpaceX's Falcon launch vehicle. Last year, SpaceX dominated the market, making 98 ...
The Bank Policy Institute (BPI) is an American public policy, research, and advocacy organization, based in Washington, D.C. The organization was formed in July 2018 following the merger of the Financial Services Roundtable and the Clearing House Association .
Rocket Lab USA, Inc. is a publicly traded aerospace manufacturer and launch service provider. [10] Its Electron orbital rockets launches small satellites , and has launched 53 times as of 2024. A sub-orbital Electron variant called HASTE (Hypersonic Accelerator Suborbital Test Electron) serves other needs. [ 11 ]
A Chinese artificial intelligence company called DeepSeek is grabbing America's attention — and sending a shock wave through Wall Street — due to its new tech, which some experts say rivals ...
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