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Although metastatic or recurrent lung cancer is difficult to be completely cured with modern medical technology, metronomic therapy is feasible as a palliative therapy by reducing tumor burden and improving patients' quality of life. Future research is expected to be experimenting effects of combinations with vinorelbine and other treatments. [21]
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
There are a few possible causes of resistance in cancer, one of which is the presence of small pumps on the surface of cancer cells that actively move chemotherapy from inside the cell to the outside. Cancer cells produce high amounts of these pumps, known as p-glycoprotein, in order to protect themselves from chemotherapeutics. Research on p ...
Monomethyl auristatin E is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.The linker to the monoclonal antibody is stable in extracellular fluid, but is cleaved by cathepsin once the conjugate has entered a tumor cell, thus activating the antimitotic mechanism.
The UK Birmingham Chemotherapy cancer COVID-19 project analysed the utility of testing every patient on chemotherapy for COVID-19 using PCR nasopharyngeal swab screening. [25] This was the first study in the world to show the clinical utility of screening for COVID-19 to prevent outbreaks amongst highly vulnerable patients who were ...
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]