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Pyometra or pyometritis is a uterine infection. Though it is most commonly known as a disease of the unaltered female dog, it is also a notable human disease. It is also seen in female cattle, horses, goats, sheep, swine, cats, rabbits, hamsters, ferrets, rats and guinea pigs.
Pseudopregnancy is a normal physiologic process that occurs in female dogs. It is seen 45–60 days after a normal estrous (heat) period. After ovulation, progesterone levels rise. Pseudopregnancy happens when the progesterone levels begin to fall as decreasing progesterone leads to an increase of the hormone prolactin. Prolactin is responsible ...
Diestrus lasts approximately 56 to 60 days in a pregnant female, and 60 to 100 days in a non-pregnant female. During both of these periods, progesterone levels are high. Because the hormonal profile of a pregnant female and a female in diestrus are the same, sometimes a non-pregnant female will go through a period of pseudopregnancy.
Proligestone, also known as 14α,17α-propylidenedioxyprogesterone or as 14α,17α-dihydroxyprogesterone cyclic acetal with propionaldehyde, as well as 14α,17α-propylidenedioxypregn-4-ene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone and 17α-hydroxyprogesterone.
The use of progesterone tests in dog breeding to pinpoint ovulation is becoming more widely used. There are several tests available but the most reliable test is a blood test with blood drawn by a veterinarian and sent to a lab for processing. Results can usually be obtained with 24 to 72 hours.
The most common form of sterilization in dogs and cats is surgical, spaying in females and castration in males. Non-surgical fertility control can either result in sterilization or temporary contraception and could offer a cheaper way to keep wild dog and cat populations under control. As of 2019, only contraceptives are commercially available.