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  2. Colchicine - Wikipedia

    en.wikipedia.org/wiki/Colchicine

    Colchicine has a narrow therapeutic index, so overdosing is a significant risk. Common side effects of colchicine include gastrointestinal upset, particularly at high doses. [13] Severe side effects may include pancytopenia (low blood cell counts) and rhabdomyolysis (damage to skeletal muscle), and the medication can be deadly in overdose. [11]

  3. Disulfiram-like drug - Wikipedia

    en.wikipedia.org/wiki/Disulfiram-like_drug

    A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover-like symptoms among others.

  4. Pharmacodynamics - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics

    The mechanism of drug action and adverse drug reaction is either physiochemical property based and biochemical based. Adverse drugs reactions can be classified as either idiosyncratic (type B) or intrinsic (type A). Idiosyncratic toxicity is not dosage dependent and defy the mass-action relationship.

  5. Adverse drug reaction - Wikipedia

    en.wikipedia.org/wiki/Adverse_drug_reaction

    Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.

  6. Common Causes of Arthritis for Women (& How to Treat It) - AOL

    www.aol.com/common-causes-arthritis-women-treat...

    Colchicine to treat or prevent gout attacks. Antibiotics for bacterial infections. Steroids to decrease inflammation. Your healthcare provider may also use injections in the affected joint to ...

  7. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Colchicine is an alternative for those unable to tolerate NSAIDs. [20] At high doses, side effects (primarily gastrointestinal upset) limit its usage. [98] At lower doses, which are still effective, it is well tolerated. [39] [99] [96] [97] Colchicine may interact with other commonly prescribed drugs, such as atorvastatin and erythromycin ...

  8. Liberals accuse elderly husband of US senator of snubbing ...

    www.aol.com/news/liberals-accuse-elderly-husband...

    Liberal netizens tore into the elderly husband of Sen. Deb Fischer (R-Neb.) for appearing to turn down Vice President Kamala Harris’ handshake last week, but viral footage that swirled online ...

  9. Toxic epidermal necrolysis - Wikipedia

    en.wikipedia.org/wiki/Toxic_epidermal_necrolysis

    Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a type of severe skin reaction. [2] Together with Stevens–Johnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. [2] Early symptoms include fever and flu-like symptoms. [2] A few days later the skin begins to blister and peel forming painful raw ...

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