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Bicuspid aortic valves are the most common cardiac valvular anomaly, occurring in 1–2% of the general population. It is twice as common in males as in females. [23] Bicuspid aortic valve is a heritable condition, with a demonstrated association with mutations in the NOTCH1 gene. [24] Its heritability is as high as 89%. [25]
Normal aortic valve is tricuspid. Five types of bicuspid valve are shown, with Type 1 being most prevalent. Bicuspid valve forms when the tissue surrounding one of the cusps (leaflets) of the valve fuse during fetal development. This developmental anomaly can have either negative or no effect on the individual.
Mitral valve or bicuspid valve, between the left atrium and left ventricle; Two semilunar valves to prevent the backflow of blood into the ventricle: Pulmonary valve, located at the opening between the right ventricle and the pulmonary trunk; Aortic valve, located at the opening between the left ventricle and the aorta.
Heart bicuspid aortic valve anatomy: Date: 23 December 2006: Source: Patrick J. Lynch, medical illustrator: Author: Patrick J. Lynch, medical illustrator: Permission (Reusing this file) Creative Commons Attribution 2.5 License 2006
Aortic valve repair or aortic valve reconstruction describes the reconstruction of both form and function of the native and dysfunctioning aortic valve. Most frequently it is applied for the treatment of aortic regurgitation. It can also become necessary for the treatment of aortic aneurysm, or less frequently for congenital aortic stenosis. [8]
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
Thus, a bicuspid valve is created which results in near-normal function of the aortic valve. The most reproducible concept is the creation of a bicuspid aortic valve with two normal commissures and two cusps. Tissue of the aortic valve is removed or detached from the aorta in places where it is clearly abnormal.
A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century. [1] [2] In the Wiggers diagram, the X-axis is used to plot time subdivided into the cardiac phases, while the Y-axis typically contains the following on a single grid: Blood pressure. Aortic ...
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