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Domperidone, sold under the brand name Motilium among others, is a dopamine antagonist medication which is used to treat nausea and vomiting and certain gastrointestinal problems like gastroparesis (delayed gastric emptying). It raises the level of prolactin in the human body and is used off label to induce and promote breast milk production.
A galactagogue, or galactogogue (from Greek: γάλα [γαλακτ-], milk, + ἀγωγός, leading), also known as a lactation inducer or milk booster, is a substance that promotes lactation in humans and other animals. [1] [2] It may be synthetic, plant-derived, or endogenous. They may be used to induce lactation and to treat low milk supply.
[26] [27] Research has indicated that such breast milk is nutritionally comparable to both the milk of naturally lactating and induced lactating cisgender women. [28] Domperidone is a drug that can induce lactation. [29] [30]
Breast milk fortification refers to the addition of nutrients such as proteins, oligosaccharides, or cytokines into breast milk to supplement the natural contents of the milk. [2] [3] [4] This practice is common in babies that have been born prematurely, with a major goal of this practice being growth promotion. [8]
In this video, a mother uses breast compression during a feed to increase the flow of milk (1 minute, 37 seconds) Using a breast pump can maintain and improve milk supply if the baby is unable to nurse effectively. Attempts to increase milk supply should begin promptly as the longer low supply continues, the more difficult it is to reverse. [2]
[5] [6] [7] Mammoplasia may be due to breast engorgement, which is temporary enlargement of the breasts caused by the production and storage of breast milk in association with lactation and/or galactorrhea (excessive or inappropriate production of milk). [8] Mastodynia (breast tenderness/pain) frequently co-occurs with mammoplasia. [9] [10]
The anti-inflammatory components in breast milk are those bioactive substances that confer or increase the anti-inflammatory response in a breastfeeding infant. [ 1 ] Anti-inflammatory Components of Breastmilk
A sharp increase in citrate and lactose concentration; [8] [9] Plasma α-lactalbumin levels peak; [8] and; Decreased breast milk sodium concentration. [10] [11] Note that delayed onset of lactogenesis II is distinct from low milk supply, where there is a normal onset of lactation, but breast milk is produced in small and insufficient amounts. [12]