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A small proportion of humans show partial or apparently complete innate resistance to HIV, the virus that causes AIDS. [1] The main mechanism is a mutation of the gene encoding CCR5, which acts as a co-receptor for HIV. It is estimated that the proportion of people with some form of resistance to HIV is under 10%. [2]
As of July 2017, the WHO is implementing the Global Action Plan on HIV drug resistance 2017–2021. It is a 5-year initiative intended to help countries around the world manage HIV drug resistance. [19] Among treatment methods, the World Health Organization acknowledges the importance of successful first-line treatments. [18]
Studies in Cameroon and the DRC in the 1980s and 1990s showed a lower prevalence of HIV in Pygmy populations than among neighboring groups, but recent increases have been recorded. One study found that the HIV prevalence among the Baka Pygmies in eastern Cameroon rose from 0.7 percent in 1993 to 4 percent in 2003. [48]
Resistance ranged from 3.9% to 8.6% and reached 19.6% among people who have received and transitioned to a dolutegravir-containing antiretroviral therapy (ART) regimen to combat high HIV viral loads.
Research shows that people without well working copies of CCR5 are either immune or resistant to HIV. The researchers’ goal for the trial was just that: To make babies who would never get HIV ...
As of 2014, the Uganda Bureau of Statistics estimates that there are approximately 6,700 Batwa people in Uganda, comprising 0.2% of the country's population. [ 3 ] : 6 This estimation is higher than that found in the 2002 National Population and Housing Census, which estimated their population to be 3,500.
A family from a Ba Aka pygmy village. The term pygmy, as used to refer to diminutive people, comes via Latin pygmaeus from Greek πυγμαῖος pygmaîos, derived from πυγμή pygmḗ, meaning "short cubit", or a measure of length corresponding to the distance from the elbow to the first knuckle of the middle finger, meant to express pygmies' diminutive stature.
Scientific evidence confirms the first arrival and subsequent increase of human settlers on the island during this period, but the pygmy theory has not been proven. Stories about the Vazimba form a significant element in the cultural history and collective identity of the Malagasy people , ranging from the historical to the supernatural ...