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Conditions in which there is poor blood flow to the systemic circulation, such as coarctation of the aorta suggests that the body does not receive the oxygenated blood it requires with resultant cyanosis. [11] The five most common cyanotic heart defects that may result in Blue Baby Syndrome include the following:
This results in a major risk of methemoglobinemia caused by nitrates ingested in drinking water, [13] dehydration (usually caused by gastroenteritis with diarrhea), sepsis, or topical anesthetics containing benzocaine or prilocaine resulting in blue baby syndrome. Nitrates used in agricultural fertilizers may leak into the ground and may ...
The mother’s immune system reacts to the Rh-positive red blood cells the same way that it would respond to something like a virus or bacteria, activating B cells — a type of white blood cell that is key to the triggering of an immune response. These activated B cells then differentiate into plasma cells, which produce anti-D antibodies.
Cyanosis is the change of body tissue color to a bluish-purple hue, as a result of decrease in the amount of oxygen bound to the hemoglobin in the red blood cells of the capillary bed. [1] Cyanosis is apparent usually in the body tissues covered with thin skin , including the mucous membranes , lips, nail beds , and ear lobes. [ 1 ]
The structure of cytochrome b5 reductase, the enzyme that converts methemoglobin to hemoglobin. [1]Methemoglobin (British: methaemoglobin, shortened MetHb) (pronounced "met-hemoglobin") is a hemoglobin in the form of metalloprotein, in which the iron in the heme group is in the Fe 3+ state, not the Fe 2+ of normal hemoglobin.
Prior to the development of the Senning procedure in the 1950s, blue baby syndrome from transposition was usually fatal. The defect causes blood from the lungs to flow back to the lungs and blood from the body to flow back to the body. As a result, the babies are blue at birth because of insufficient blood oxygen. [2]
A baby’s “beautiful big blue eyes”, which were complimented by everyone, turned out to be a symptom of a condition causing blindness. Louise Bice, 34, was stunned when her daughter, Aretria ...
She had a condition called Tetralogy of Fallot, one of the primary congenital defects that lead to blue baby syndrome. In this condition, defects in the great vessels and wall of the heart lead to a chronic lack of oxygen in the blood. In Eileen's case, this made her lips and fingers turn blue, with the rest of her skin having a very faint blue ...