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Common side effects of tizanidine include dry mouth, sleepiness, weakness, and dizziness. [5] Serious side effects may include low blood pressure, liver problems, psychosis, and QT prolongation. [5] It is unclear if use in pregnancy and breastfeeding is safe. [6] It is an α 2-adrenergic agonist, but how it works is not entirely clear. [5]
In certain cases, elderly patients' previous interactions with phenothiazine derivatives or pre-existing neuroleptic treatment may have contributed to dyskinesia at the administration of hydroxyzine due to hypersensitivity caused by prolonged treatment, [23] and therefore some contraindication is given for short-term administration of ...
Two widely touted Alzheimer’s drugs have been shown to enable patients to remain in their homes for longer periods of time. Those medications, however, are not without their risks and side effects.
Cyclobenzaprine has been found not to be inferior to tizanidine, orphenadrine, and carisoprodol in the treatment of acute lower back pain, although none have been proven to be effective for long-term use (beyond two weeks of treatment).
Dementia impacts almost 10% of older adults in the U.S. While scientists haven’t pinpointed exactly what causes it, research is slowly identifying new factors, like diet, that may play a role in ...
The known risks and benefits of semaglutide medicines are described in their FDA-approved product labeling and we work closely with authorities and regulatory bodies worldwide to continuously ...
Eperisone has not been established as definitely safe for paediatric use, therefore its use in paediatrics cannot be recommended without further study. [6] If elderly patients are treated with eperisone, a reduced dose is recommended, and the patient should be closely monitored for signs of physiological hypofunction during treatment. [6]
[medical citation needed] Elucidation of the exact mechanism of action is ongoing but there is limited study due to the existence of more effective, safe muscle relaxants (e.g., diazepam, cyclobenzaprine, tizanidine), greatly limiting the potential benefit of identifying novel compounds which share chlorzoxazone's mechanism of action.