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Denosumab, sold under the brand names Prolia among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. [11] [12] The most common side effects are joint and muscle pain in the arms or legs. [13]
Iliocostal friction syndrome most commonly occurs bilaterally as a result of spinal osteoporosis. [2] Osteoporosis is a condition in which the bone density and quality deteriorates, resulting in an increased risk for fractures. More than 2 million fractures occur annually in the United States due to osteoporosis. [9]
Prolia, approved in 2010 to treat bone loss in postmenopausal women and later approved to treat men and women at high risk of fracture, brought in total third-quarter sales of $986 million.
A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
A sharp pain that may or may not shoot down your leg. Pain that radiates into other parts of the body, like your abdomen, hips, buttocks, legs, or even feet ... osteoporosis, osteoarthritis ...
How much does Prolia cost? According to the Prolia website, the average cost is $1,786.12 per injection. However, Original Medicare typically covers 80% of the cost of Prolia. This means the ...
Meralgia paresthetica or meralgia paraesthetica is pain or abnormal sensations in the outer thigh not caused by injury to the thigh, but by injury to a nerve which provides sensation to the lateral thigh. Meralgia paresthetica is a specific instance of nerve entrapment. [5] The nerve involved is the lateral femoral cutaneous nerve (LFCN).
Typical factors aggravating the back pain of pregnancy include standing, sitting, forward bending, lifting and walking. Back pain in pregnancy may also be characterized by pain radiating into the thigh and buttocks, nighttime pain severe enough to wake the patient, pain that is increased at night or pain that is increased during the daytime. [78]