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Found in the lowest layer of the epidermis, the stratum basale, basal cells continuously divide in order to replenish the squamous cells that make up the skin's surface. [6] Every time a basal cell divides, it creates two daughter cells, one is an identical basal cell, and the other is a new somatic cell that undergoes terminal differentiation .
The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the external covering of skin in mammals. The stratum basale is a single layer of columnar or cuboidal basal cells. The cells are attached to each other and to the overlying stratum spinosum cells by ...
Histologic image of the epidermis with its layers named in white text.. The Malpighian layer (stratum mucosum or stratum malpighii) of the epidermis is generally defined as both the stratum basale (basal layer) and the thicker stratum spinosum (spinous layer/prickle cell layer) immediately above it as a single unit, [1] [2] although it is occasionally defined as the stratum basale specifically ...
A calcium gradient, with the lowest concentration in the stratum basale and increasing concentrations until the outer stratum granulosum, where it reaches its maximum. Calcium concentration in the stratum corneum is very high in part because those relatively dry cells are not able to dissolve the ions. [10]
H&E stained section of human skin. The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which ...
They form several layers of the skin. Life for a keratinocyte begins at the stratum basale layer. Cells here proliferate and move through the stratum spinosum and stratum granulosum. The topmost layer is called the stratum corneum. During sloughing, it is this layer that is removed. [1]
The blood vessels in the dermis provide nourishment and waste removal from its own cells as well as from the stratum basale of the epidermis. The dermis is structurally divided into two areas: a superficial area adjacent to the epidermis, called the papillary region, and a deep thicker area known as the reticular region.
The epidermis is the most superficial layer of skin, a squamous epithelium with several strata: the stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale. [8] Nourishment is provided to these layers by diffusion from the dermis since the epidermis is without direct blood supply.