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Infective endocarditis is an infection of the inner surface of the heart (endocardium), usually the valves. [1] Signs and symptoms may include fever, small areas of bleeding into the skin, heart murmur, feeling tired, and low red blood cell count.
Nonbacterial thrombotic endocarditis (NBTE) is most commonly found on previously undamaged valves. [2] As opposed to infective endocarditis, the vegetations in NBTE are small, sterile, and tend to aggregate along the edges of the valve or the cusps. [2] Also unlike infective endocarditis, NBTE does not cause an inflammation response from the ...
The HACEK organisms are a group of fastidious Gram-negative bacteria that are an unusual cause of infective endocarditis, which is an inflammation of the heart due to bacterial infection. [1] HACEK is an abbreviation of the initials of the genera of this group of bacteria: Haemophilus , Aggregatibacter (previously Actinobacillus ...
Other species are K. indologenes, K. denitrificans (both causing endocarditis) and K. oralis found in dental plaque. One notable exception is in cases of endocarditis (heart valve infection), which can be more refractory to treatment. K. kingae is the fifth member of the HACEK group of fastidious Gram-negative bacteria that cause endocarditis ...
The bacteria initially causes a disease called Q fever, but months or sometimes years after the initial Q fever, they can develop endocarditis, but usually this is in high-risk people, like those that are immunocompromised, pregnant women, and those with pre-existing heart valve defect, which makes it tricky to diagnose unless there’s a ...
Other strains of streptococci can cause subacute endocarditis as well. These include streptococcus intermedius, which can cause acute or subacute infection (about 15% of cases pertaining to infective endocarditis). [7] Enterococci from urinary tract infections and coagulase negative staphylococci can also be causative agents. [5]
Inflammation of the heart valves due to any cause is called valvular endocarditis; this is usually due to bacterial infection but may also be due to cancer (marantic endocarditis), certain autoimmune conditions (Libman-Sacks endocarditis, seen in systemic lupus erythematosus) and hypereosinophilic syndrome (Loeffler endocarditis).
Cardiobacterium hominis was originally discovered in 1962 based on analysis of four cases of Infective endocarditis over ten months. [5] Upon its first isolation, researchers described Cardiobacterium hominis, which was unrecognized then, as a Pasteurella-like organism and categorized as group "II-D" by the Centers for Disease Control and Prevention.