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  2. Doxycycline - Wikipedia

    en.wikipedia.org/wiki/Doxycycline

    Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. [1] It is used to treat bacterial pneumonia , acne , chlamydia infections , Lyme disease , cholera , typhus , and syphilis . [ 1 ]

  3. Tetracycline antibiotics - Wikipedia

    en.wikipedia.org/wiki/Tetracycline_antibiotics

    Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.

  4. Metalloprotease inhibitor - Wikipedia

    en.wikipedia.org/wiki/Metalloprotease_inhibitor

    Thus far, Periostat (active ingredient is doxycycline hyclate) is the only MMP inhibitor that has been approved by the U.S. Food and Drug Administration (FDA). It is used for the treatment of periodontitis. Other MMP inhibitors have exhibited serious side effects during preclinical trials. These side effects are caused by insufficient selectivity.

  5. Hyclate - Wikipedia

    en.wikipedia.org/wiki/Hyclate

    A hyclate (Latin: hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate [1] [2] (·HCl· ⁠ 1 / 2 ⁠ EtOH· ⁠ 1 / 2 ⁠ H 2 O), e.g. doxycycline hyclate. [ 3 ] [ 4 ] References

  6. Tetracycline - Wikipedia

    en.wikipedia.org/wiki/Tetracycline

    Tetracycline, sold under various brand names, is an antibiotic in the tetracyclines family of medications, used to treat a number of infections, [3] including acne, cholera, brucellosis, plague, malaria, and syphilis. [3] It is available in oral and topical formulations. [4] [5] Common side effects include vomiting, diarrhea, rash, and loss of ...

  7. Metacycline - Wikipedia

    en.wikipedia.org/wiki/Metacycline

    It is used as a precursor in the industrial synthesis of doxycycline hyclate. [citation needed] It has been found to act as an agonist of the human pregnane X receptor ligand-binding domain and to induce CYP3A4 expression in vitro. [1]

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  9. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.