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Dobutamine is a medication used in the treatment of cardiogenic shock (as a result of inadequate tissue perfusion) and severe heart failure. [ 2 ] [ 3 ] It may also be used in certain types of cardiac stress tests . [ 2 ]
Cardiogenic shock leads to many harmful physiological effects. Specifically, in patients experiencing inadequate blood perfusion (with blood pressure below 80 mmHg), the American Heart Association / American College of Cardiology (ACC/AHA), recommends the use of Dobutamine and Milrinone. [75]
Pimobendan (INN, or pimobendane), sold under the brand name Vetmedin among others, is a veterinary medication. It is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects.
Use in sepsis has been explored in clinical trials, but use of an inotropic agent like dobutamine or dopexamine did not reduce mortality compared with norepinephrine or epinephrine. [15] Use of dopexamine may be harmful in sepsis [5]
Dobutamine [11] (in cardiogenic shock) is a beta-1 agonist that treats cardiac decompensation. Xamoterol [11] (cardiac stimulant) acts as a partial agonist that improves heart function in studies with cardiac failure. Xamoterol plays a role in modulating the sympathetic nervous system, but does not have any agonistic action on beta-2 adrenergic ...
“Even if there was no nicotine in the e-cigarette, there could be other components that may be harmful,” Nabbout told CNN, adding that this could be why the study saw such a “significant ...
Vitamin D and calcium are essential for overall health, but don’t reduce the risk of falls or fractures in generally healthy older adults, according to a new draft recommendation from the US ...
Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)). )). Reperfusion therapy includes drugs and su