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2. Chilblain lupus erythematosus - Wikipedia

   en.wikipedia.org/wiki/Chilblain_lupus_erythematosus

   Tacrolimus ointment and pimecrolimus cream, two topical calcineurin inhibitors, may also be useful in avoiding skin atrophy, one of the local side effects of long-term topical steroids. [14] Because calcium channel blockers like nifedipine work against vasoconstriction, they lessen erythema and pain. Giving up smoking might be taken into ...

3. Tacrolimus - Wikipedia

   en.wikipedia.org/wiki/Tacrolimus

   Tacrolimus 0.1% Ointment As an ointment , tacrolimus is used in the treatment of dermatitis (eczema), in particular atopic dermatitis , if topical corticosteroids and moisturisers fail in helping. [ 17 ] [ 18 ] It suppresses inflammation in a similar way to steroids , and is equally as effective as a mid-potency steroid.

4. Allergic contact dermatitis - Wikipedia

   en.wikipedia.org/wiki/Allergic_contact_dermatitis

   Tacrolimus ointment or pimecrolimus cream can also be used additionally to the corticosteroid creams or instead of these. Oral antihistamines such as diphenhydramine or hydroxyzine may also be used in more severe cases to relieve the intense itching via sedation. [ 20 ]

5. Dermatitis - Wikipedia

   en.wikipedia.org/wiki/Dermatitis

   Tacrolimus 0.1%. Topical immunosuppressants like pimecrolimus and tacrolimus may be better in the short term and appear equal to steroids after a year of use. [66] Their use is reasonable in those who do not respond to or are not tolerant of steroids. [67] [68] Treatments are typically recommended for short or fixed periods of time rather than ...

6. Immunosuppressive drug - Wikipedia

   en.wikipedia.org/wiki/Immunosuppressive_drug

   Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects. Contrary to ciclosporin and tacrolimus, drugs that affect the first phase of T lymphocyte activation, sirolimus affects the second phase, namely signal transduction and lymphocyte clonal proliferation.

7. 5 cancer types where screenings save the most lives - AOL

   www.aol.com/5-cancer-types-where-screenings...

   Over a 45-years span — between 1975 and 2020 — improvements in cancer screenings and prevention strategies have reduced deaths from five common cancers more than any advances in treatments ...