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Growth differentiation factor 7 (GDF7) is a protein that in humans is encoded by the GDF7 gene. [ 5 ] GDF7 belongs to the transforming growth factor beta superfamily that is specifically found in a signaling center known as the roof plate that is located in the developing nervous system of embryos .
Growth differentiation factor 11 (GDF11), also known as bone morphogenetic protein 11 (BMP-11), is a protein that in humans is encoded by the growth differentiation factor 11 gene. [5] GDF11 is a member of the Transforming growth factor beta family. [6] GDF11 acts as a cytokine and its sequence is highly conserved between in humans, mice and ...
A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation. [1] Usually it is a secreted protein or a steroid hormone .
Researchers from Oxford Population Health used data from nearly 500,000 participants in the U.K. to assess the influence of 164 environmental factors and genetic risk scores for 22 age-related ...
In factors VII, IX and X, the two cbEGF modules are preceded by an N-terminal gamma-carboxyglutamic acid (Gla) containing module (the Gla module). [15] In vitro studies on the Gla-cbEGF tandem isolated from factor X revealed a K d -value of 0.1 mM for calcium binding [ 18 ] with the free calcium blood plasma concentrations being approximately 1 ...
Epidermal Growth Factor like domain 7 (Egfl7) also known as Vascular Endothelial-statin (VE-statin) codes for a gene mostly expressed in endothelial cells. [ 6 ] [ 7 ] [ 8 ] The egfl7 gene is located on chromosomes 9 and 2 in human and mouse, respectively, and is structured in 11 exons and introns, including intron-1a and 1b which are ...
14178 Ensembl ENSG00000140285 ENSMUSG00000027208 UniProt P21781 P36363 RefSeq (mRNA) NM_002009 NM_008008 RefSeq (protein) NP_002000 NP_032034 Location (UCSC) Chr 15: 49.42 – 49.49 Mb Chr 2: 125.88 – 125.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. Function The protein encoded by this gene is ...
The keratinocyte growth factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phase of wound healing. In this phase, keratinocytes are covering the wound, forming the epithelium. KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b (FGFR2b). [1]