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Granulomatosis with polyangiitis 50-60% have ophthalmologic manifestations, which can be a presenting feature in a minority of patients. Orbital disease is the most common manifestation, and may result in proptosis , restrictive ophthalmopathy , chronic orbital pain, and in chronic cases, orbital retraction syndrome and intractable socket pain.
The prognosis for CSR is generally excellent. While immediate vision loss may be as poor as 20/200 in the affected eye, clinically, over 90% of patients regain 20/25 vision or better within 45 days. [1] Once the fluid has resolved, either spontaneously or through treatment, distortion is reduced and visual acuity improves as the eye heals.
Anosmia is the inability to perceive odor, or in other words a lack of functioning olfaction.Many patients may experience unilateral or bilateral anosmia. A temporary loss of smell can be caused by a blocked nose or infection. In contrast, a permanent loss of smell may be caused by death of olfactory receptor neurons in the nose or by brain injury in which there is damage to the
Long-term contact lens use can lead to alterations in corneal thickness, stromal thickness, curvature, corneal sensitivity, cell density, and epithelial oxygen uptake. . Other structural changes may include the formation of epithelial vacuoles and microcysts (containing cellular debris), corneal neovascularization, as well as the emergence of polymegethism in the corneal endoth
Hydrocephalus that is present from a young age can cause long-term problems with speech and language. Children can have trouble understanding complex and abstract concepts or difficulty retrieving stored information. They may also have a nonverbal learning disorder or spatial/perceptual disorders.
The main clinical features are signature language progressive difficulties with speech production. There can be problems in different parts of the speech production system, hence patients can present with articulatory breakdown, phonemic breakdown (difficulties with sounds) and other problems. However, it is rare for patients to have just one ...
Right hemisphere damage rarely causes FAS. The majority of patients with FAS usually present other speech disorders, such as: mutism, aphasia, dysarthria, agrammatism and apraxia of speech. [13] Neurolinguist Harry Whitaker [14] first coined the term foreign accent syndrome in 1982. He originally proposed some criteria that must be present in ...
Implicated orbital disorders include optic gliomas, meningiomas, hemangiomas, lymphangiomas, dermoid cysts, carcinoma, lymphoma, multiple myeloma, inflammatory orbital pseudotumor, and thyroid ophthalmopathy. Patients often have bulging out of the eye (proptosis) with mild color deficits and almost normal vision with disc swelling.