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Skin sloughing is the process of shedding dead surface cells from the skin. It is most associated with cosmetic skin maintenance via exfoliation , but can also occur biologically or for medical reasons.
An eschar (/ ˈ ɛ s k ɑːr /; Greek: ἐσχάρᾱ, romanized: eskhara; Latin: eschara) is a slough [1] or piece of dead tissue that is cast off from the surface of the skin, particularly after a burn injury, but also seen in gangrene, ulcer, fungal infections, necrotizing spider bite wounds, tick bites associated with spotted fevers and exposure to cutaneous anthrax.
Sloughing of the epidermis and exposure of the dermal layer clinically characterize moist desquamation. Moist desquamation presents as tender, red skin associated with serous exudate , hemorrhagic crusting, and has the potential for development of bullae .
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
A dragonfly in its radical final moult, metamorphosing from an aquatic nymph to a winged adult.. In biology, moulting (British English), or molting (American English), also known as sloughing, shedding, or in many invertebrates, ecdysis, is a process by which an animal casts off parts of its body to serve some beneficial purpose, either at specific times of the year, or at specific points in ...
The histological picture involves thinner, weaker attachments of the skin lesion itself to the normal skin – resulting in easier dislodgement. The formation of new blisters upon slight pressure (direct Nikolsky) and shearing of the skin due to rubbing (indirect Nikolsky) is a sign of pemphigus vulgaris, albeit not a 100% reliable diagnosis. [ 8 ]
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Sloughing may refer to: Sloughing, in biology, shedding or casting off dead tissue Skin sloughing, shedding dead surface cells off the skin; Soil sloughing, a type of soil behavior; Sloughing (biofilms), shedding of the biofilm in certain wastewater treatment units, particularly trickling filters and rotating biological contactors.