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Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
NSAIDs aside from (low-dose) aspirin are associated with a doubled risk of heart failure in people without a history of cardiac disease. [66] In people with such a history, use of NSAIDs (aside from low-dose aspirin) was associated with a more than 10-fold increase in heart failure. [67]
meloxicam – nonsteroidal anti-inflammatory drug (NSAID) metacam – used to reduce inflammation and pain; methimazole – used in treatment of hyperthyroidism; methocarbamol - muscle relaxant used to reduce muscle spasms associated with inflammation, injury, intervertebral disc disease, and certain toxicities
However, the task force added that there is a “small net benefit” in taking aspirin to lower cardiovascular disease risk in people between the ages of 40 and 59 with a higher risk of ...
However, more recent trials were not able to replicate similar outcomes using low dose aspirin in low body weight (<70 kg) in specific subset of population studied i.e. elderly and diabetic population, and more evidence is required to study the effect of high dose aspirin in high body weight (≥70 kg). [108] [109] [110]