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The disease was renamed 'pantothenate kinase-associated neurodegeneration' or PKAN by Zhou et al. (2001) [3] who suggested the name to avoid misinterpretation and to better reflect the true nature of the disorder. Most recently Pellecchia et al. (2005) published a report of 16 patients affected by PKAN, confirmed by genetic analysis.
A systematic review of placebo-controlled trials investigating tDCS treatment for major depressive disorder was published 2020. [12] The meta-analysis collated results across nine eligible studies (572 participants) up until December 2018 to estimate odds ratio (OR) and number needed to treat (NNT) of response and remission, and depression ...
The exact pathophysiological causes of the disease are currently unclear, but there are developing theories. [8] Spongy degeneration can be diagnosed with neuroimaging techniques and urine examination. [9] There is no current treatment for spongy degeneration, but research utilising gene therapy to treat the disease is underway. [8]
Brad McGarry poses with then-Mercyhurst University freshman Kaitlyn Stark in this 2015 file photo. Stark was a student in Autism Initiative at Mercyhurst, which McGarry coordinated.
MRI studies have found a smaller brain volume and larger ventricles in people with schizophrenia – however researchers do not know if the shrinkage is from the schizophrenia or from the medication. [ 158 ] [ 159 ] The hippocampus and thalamus have been shown to be reduced in volume; and the volume of the globus pallidus is increased.
Encephalopathy is a difficult term because it can be used to denote either a disease or finding (i.e., an observable sign in a person). [citation needed] When referring to a finding, encephalopathy refers to permanent (or degenerative) [11] brain injury, or a reversible one. It can be due to direct injury to the brain, or illness remote from ...
The diagnosis is usually made by a brain scan , in which areas of swelling can be identified. The treatment for PRES is supportive: removal of the cause or causes and treatment of any of the complications, such as anticonvulsants for seizures. PRES may be complicated by intracranial hemorrhage, but this is relatively rare. The majority of ...
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, [1] are a group of progressive, incurable, and fatal conditions that are associated with the prion hypothesis and affect the brain and nervous system of many animals, including humans, cattle, and sheep.