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HIV is the cause of the spectrum of disease known as HIV/AIDS. HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90]
A good CD8 + T cell response has been linked to slower disease progression and a better prognosis, though it does not eliminate the virus. [3] During the acute phase, HIV-induced cell lysis and killing of infected cells by cytotoxic T cells accounts for CD4 + T cell depletion, although apoptosis may also be a factor.
The management of HIV/AIDS typically involves the use of multiple antiretroviral drugs. In many parts of the world, HIV has become a chronic condition, with progression to AIDS increasingly rare. HIV latency and the resulting viral reservoir in CD4 + T cells, dendritic cells, and macrophages is the main barrier to eradication of the virus. [19 ...
Original file (1,283 × 1,656 pixels, file size: 984 KB, MIME type: application/pdf, 8 pages) This is a file from the Wikimedia Commons . Information from its description page there is shown below.
The 1994 expanded World Health Organization AIDS case definition [1] came around through the developments in the understanding of the spectrum of severe HIV-related illness both in developed and developing countries, and the increased availability of laboratory diagnostic methods, a meeting was convened in Geneva, Switzerland by the World Health Organization Global Programme on AIDS to review ...
The genome and proteins of HIV (human immunodeficiency virus) have been the subject of extensive research since the discovery of the virus in 1983. [1] [2] "In the search for the causative agent, it was initially believed that the virus was a form of the Human T-cell leukemia virus (HTLV), which was known at the time to affect the human immune system and cause certain leukemias.
WHO Disease Staging System for HIV Infection and Disease was first produced in 1990 by the World Health Organization [1] and updated in 2007. [2] It is an approach for use in resource limited settings and is widely used in Africa and Asia and has been a useful research tool in studies of progression to symptomatic HIV disease .
According to Duesberg, common diseases are easily misdiagnosed as AIDS in Africa because "the diagnosis of African AIDS is arbitrary" and does not include HIV testing. [1] A definition of AIDS agreed upon in 1985 by the World Health Organization in Bangui did not require a positive HIV test, but since 1985, many African countries have added ...
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